Skip to content | Change text size
 

Dr Stephen J Headey

Image of Dr Stephen J Headey

Research Fellow

BSc(Hons) University of Melbourne
PhD University of Melbourne

Phone: +61 3 9903 9117
Fax: +61 3 9903 9581
Email: stephen.headey@pharm.monash.edu.au

Medicinal Chemistry and Drug Action, Monash Institute of Pharmaceutical Sciences

Research interests

  • Protein structure determination by NMR
  • Protein-protein and protein-drug interactions by NMR
  • Drug discovery and lead optimisation

Representative publications

  1. Claridge JK, Headey SJ, Chow JY, Schwalbe M, Edwards PJ, Jeffries CM, Venugopal H, Trewhella J, Pascal SM. A picornaviral loop-to-loop replication complex. J Struct Biol. 2009 (in press)
  2. Headey SJ, Vom A, Simpson JS and Scanlon MJ. Backbone assignments of the 34 kDa ketopantoate reductase from E. coli. J Biom NMR Assign. 2008; 2:93-96
  3. Headey SJ, Huang H, Claridge JK, Soares GA, Dutta K, Schwalbe M, Yang D, Pascal SM. NMR structure of stem-loop D from human rhinovirus-14. RNA. 2007; 13:351-360.
  4. Bach LA, Headey SJ, Norton RS. IGF-binding proteins - the pieces are falling into place. Trends Endocrinol Metab. 2005; 16:228-34
  5. Headey SJ, Keizer DW, Yao S, Brasier G, Kantharidis P, Bach LA, Norton RS. C-terminal domain of insulin-like growth factor (IGF) binding protein-6: structure and interaction with IGF-II. Mol Endocrinol. 2004; 18:2740-2750
  6. Headey SJ, Leeding KS, Norton RS, Bach LA. Contributions of the N- and C-terminal domains of IGF binding protein-6 to IGF binding. J Mol Endocrinol. 2004; 33:377-386.
  7. Headey SJ, Keizer DW, Yao S, Wallace JC, Bach LA, Norton RS. Binding site for the C-domain of insulin-like growth factor (IGF) binding protein-6 on IGF-II; implications for inhibition of IGF actions. FEBS Lett. 2004; 18:19-22
  8. Yao S, Headey SJ, Keizer DW, Bach LA, Norton RS. C-terminal domain of insulin-like growth factor (IGF) binding protein 6: conformational exchange and its correlation with IGF-II binding. Biochemistry. 2004; 43:11187-11195.