Skip to content | Change text size
 

Dr John Haynes

Photo of Dr Haynes

Senior Lecturer
Stem Cell Biology group leader, Medicinal Chemistry and Drug Action, Monash Institute of Pharmaceutical Sciences

BSc(Hons)  Monash University
PhD Monash University

Telephone: +61 3 9903 9072
Fax:  +61 3 9903 9638
Email: john.haynes@pharm.monash.edu.au

Medicinal Chemistry and Drug Action, Monash Institute of Pharmaceutical Sciences

Research interests

  • Stem cell differentiation.
  • Stem cell derived neuron and cardiac myocyte function.
  • Prostate growth
  • Calcium utilization in neurons and prostate

Education

Lecture in:

  • Bachelor of Pharmaceutical Sciences: renal physiology, pharmacology and second messenger signalling, Neurodegeneration (Parkinson’s disease)
  • Bachelor of Pharmacy: renal physiology and diuretic action

Representative publications

  1. Pouton CW, Haynes JM.  Embryonic stem cells as a source of models for drug discovery.  Nature Reviews Drug Discovery. 2007; 6(8):605-616.
  2. Raye WS, Touchon-Danguy N, Pouton CW, Haynes JM. Heterogeneous populations of dopaminergic neurons derived from mouse embryonic stem cells: pharmacological phenotyping based on receptor expression. Eur J Neurosci. 2007; 25(7):1961-1970.
  3. Nguyen S, Prakash R, Anderson C, Frydenberg M, Haynes JM. Sex steroids modulate a1-adrenoceptor-stimulated Ca2+ influx in human cultured prostatic stromal cells.  Prostate. 2007; 67(1):74-82.
  4. Haynes JM, Cook AL.  Protein kinase G-induced activation of KATP channels reduces contractility of human prostate tissue.  Prostate. 2006; 66(4):377-385.
  5. Lang RJ, Haynes JM, Kelly J, Johnson J, Mulholland EM Baker L, Munsie M, Pouton CW. Electrical and neurotransmitter activity of mature neurons derived from mouse embryonic stem cells by sox-1 lineage selection and directed differentiation.  Eur J Neurosci. 2004; 20:3209-3221.
  6. Preston AJ, Frydenberg M, Haynes JM.  A1 and A2A adenosine receptor modulation of α1-adrenoceptor-mediated contractility in human cultured prostatic stromal cells.  Br J Pharmacol. 2004; 141:302-310.
  7. Cook AL, Frydenberg M, Haynes JM.  Protein kinase G II-mediated proliferative effects in human cultured prostatic stromal cells. Cell Sig. 2004; 16:253-261.
  8. Haynes JM, Frydenberg M, Majewski H.  Testosterone-stimulated proliferation in human cultured prostatic stromal cells: regulation through a protein kinase Ca-dependent pathway.  Cell Sig. 2001; 13:1-7.
  9. Haynes JM, Hill SJ. b-Adrenoceptor-mediated inhibition of a1-adrenoceptor-mediated and field-stimulation-induced contractile responses in the prostate of the guinea-pig.  Br J Pharmacol. 2001; 122:1067-1074.
  10. Haynes JM, Hodgson WC, Cooper ME. Rat amylin and salmon calcitonin mediated pressor responses in the anaesthetised rat: the effects of peptide antagonists.  Diabetalogia. 1997; 40:256-261.
  11. Haynes JM, Cooper ME.  Adrenomedullin and calcitonin gene related peptide in the rat isolated kidney and in the anaesthetised rat: in vitro and in vivo effects.  Eur J Pharmacol. 1995; 280:91-94.

External appointments

  • Editorial board: Clinical and Experimental Pharmacology and Physiology