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Dr Ian Larson

Picture of Dr Ian C. Larson

Senior lecturer

BSc(Hons) University of Melbourne
PhD University of Melbourne

Telephone: +61 3 9903 9570
Fax: +61 3 9903 9583
Email: ian.larson@pharm.monash.edu.au

Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences

Research interests

  • Particle-based delivery systems
  • Novel delivery systems for improved pulmonary drug delivery
  • Powder technology

Education

Representative publications

  1. Ta HT, Han H, Larson IC, Dass C, Dunstan D. Chitosan-dibasic orthophosphate hydrogel: a potential drug delivery system. International Journal of Pharmaceutics. 2009; 371:134-141.
  2. Ta HT, Dass C, Larson IC, Choong PFM, Dunstan DE.  A chitosan-dipotassium orthosphosphate hydrogel for the delivery of doxorubicin in the treatment of osteosarcoma. Biomaterials. 2009; 30:3605-3613.
  3. Adi H, Larson I, Stewart P. Influence of the polydispersity of the added fine lactose on the dispersion of salmeterol xinafoate from mixtures for inhalation. Eur. J. Pharm. Sci. 2009; 2-3:265-274.
  4. Das S, Larson I, Young P, Stewart P. Influence of storage relative humidity on the dispersion of salmeterol xinafoate powders for inhalation. J. Pharm Sci. 2009; 98(3):1015-1027.
  5. Dong Y, Dong A, Larson I, Rappolt M, Amenitsch H, Hanley T, et.al. Impurities in commercial phytantriol significantly alter its lyotropic liquid-crystalline phase behavior. Langmuir. 2008; 24(13):6998-7003.
  6. Adi H, Larson I, Chiou H, Young P, Traini D, Stewart P. Role of agglomeration in the dispersion of salmeterol xinafoate from mixtures for inhalation with differing drug to fine lactose ratios. J. Pharm Sci. 2008; 97(8):3140-3152.
  7. Adi H, Larson I, Stewart P. Laser diffraction particle sizing of cohesive lactose powders Powder Tech. 2007; 179:90-94.
  8. Adi H, Larson I, Stewart P. Adhesion and redistribution of salmeterol xinafoate particles in sugar-based mixtures for inhalation. Int. J. Pharm. 2007; 337:229-238.
  9. Dong D, Larson I, Hanley T, Boyd B. Bulk and Dispersed Aqueous Phase Behavior of Phytantriol: Effect of Vitamin E Acetate and F127 Polymer on Liquid Crystal Nanostructure Y. Langmuir. 2006; 22:9512-9518.
  10. Adi H, Larson I, Chiou H, Young P, Traini D, Stewart P. Agglomerate Strength and Dispersion of Salmeterol Xinafoate from Powder Mixtures for Inhalation. Pharm Res. 2006; 23(11):2556-2565.
  11. Ralston J, Larson I, Rutland M, Feiler A, Kleijn M. Atomic Force Microscopy and Direct Surface Force Measurements. Pure App. Chem. 2005; 77(12):2149-2170.
  12. Islam N, Stewart PJ, Larson I, Hartley P. Lactose surface modification by decantation-are drug-fine lactose ratios the key to better dispersion of salmeterol xinafoate from lactose interactive mixtures? Pharm. Res. 2004; 21(3):492-499.
  13. Larson I, Drummond CJ, Chan DYC, Grieser F. Direct force measurements between TiO2 surfaces. J Am Chem Soc. 1993; 115:11885-90.
  14. Hartley PG, Larson I, Scales PJ. Electrokinetic and direct force measurements between silica and mica surfaces in dilute electrolyte solutions. Langmuir. 1997; 13:2207-14.
  15. Larson I, Drummond CJ, Chan DYC, Grieser F. Direct force measurements between dissimilar metal-oxides. J Phys Chem. 1995; 99:2114-18.
  16. Larson I, Drummond CJ, Chan DYC, Grieser F. Direct force measurements between silica and alumina Langmuir. 1997; 13:2109-12.
  17. Sader J, Larson I, Mulvaney P, White LR. Method for the calibration of atomic force microscope cantilevers. Rev Sci Instrum. 1995;66:3789-98.
  18. Milling AJ, Mulvaney P, Larson I. Direct measurement of repulsive van der Waals interactions using an atomic force microscope. J Colloid & Interface Sci. 1996;180:460-5.
  19. Larson I, Drummond CJ, Chan DYC, Grieser F. Use of atomic force microscope force measurements to monitor citrate displacement by amines on gold in aqueous solution. Langmuir. 1997;13:2429-31.
  20. Attard P, Antelmi D, Larson I. A comparison of the zeta potential with the diffuse layer potential from charge titration. Langmuir. 2000; 16:1542-52. 
  21. Larson I, Attard P. The Surface Charge of Silver Iodide and Several Metal Oxides. Are All Surfaces Nernstian? J. Colloid & Interface Sci. 2000; 227:152-163.
  22. Feiler A, Attard P, Jenkins P, Larson I. A quantitative study of interaction forces and friction in aqueous colloidal systems. Langmuir. 2000; 16:10269-77.

External appointments

  • Victorian representative, Colloid and Surfaces Division, Royal Australian Chemical Institute