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Dr Ian Larson

Picture of Dr Ian C. Larson

Senior lecturer

BSc(Hons) University of Melbourne
PhD University of Melbourne

Telephone: +61 3 9903 9570
Fax: +61 3 9903 9583
Email: ian.larson@monash.edu

Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences

Research interests

  • Particle-based delivery systems
  • Novel delivery systems for improved pulmonary drug delivery
  • Powder technology

Education

  • Developer of Pharmatopia – a collaborative virtual world learning tool
  • Second Year Colloid Chemistry
  • Third year Formulation Chemistry
  • Major teaching expertise: colloid and surface chemistry, polymer chemistry, formulation chemistry

Representative publications

  1. Dube A, Nicolazzo J, Larson I. Chitosan nanoparticles enhance the intestinal absorption of the green tea catechins (+)-catechin and (-)-epigallocatechin gallate. European Journal of Pharmaceutical Sciences. 2010: 41:219-225.
  2. Dube A, Ng K, Nicolazzo J, Larson I. Effective use of reducing agents and nanoparticle encapsulation in stabilizing catechins in alkaline solution. Food Chemistry. 2010; 122:662-667.
  3. Ta HT, Han H, Larson I, Dass C, Dunstan D. Chitosan-dibasic orthophosphate hydrogel: a potential drug delivery system. International Journal of Pharmaceutics. 2009; 371:134-141.
  4. Ta HT, Dass C, Larson I, Choong PFM, Dunstan DE A chitosan-dipotassium orthosphosphate hydrogel for the delivery of doxorubicin in the treatment of osteosarcoma. Biomaterials. 2009; 30:3605-3613.
  5. Adi H, Larson I, Stewart P. Influence of the polydispersity of the added fine lactose on the dispersion of salmeterol xinafoate from mixtures for inhalation. European Journal of Pharmaceutical Sciences. 2009; 2-3:265-274.
  6. Das S, Larson I, Young P, Stewart PInfluence of storage relative humidity on the dispersion of salmeterol xinafoate powders for inhalation. Journal of Pharmaceutical Sciences. 2009; 98(3):1015-1027.
  7. Dong Y, Dong A, Larson I, Rappolt M, Amenitsch H, Hanley T, et.al.
  8. Adi H, Larson I, Chiou H, Young P, Traini D, Stewart P.Role of agglomeration in the dispersion of salmeterol xinafoate from mixtures for inhalation with differing drug to fine lactose ratios. Journal of Pharmaceutical Sciences. 2008; 97(8):3140-3152.
  9. Adi H, Larson I, Stewart P Laser diffraction particle sizing of cohesive lactose powders. Powder Technology. 2007; 179:90-94.
  10. Adi H, Larson I, Stewart P. Adhesion and redistribution of salmeterol xinafoate particles in sugar-based mixtures for inhalation. International Journal of Pharmaceutics. 2007; 337:229-238.
  11. Dong D, Larson I, Hanley T, Boyd B. Bulk and Dispersed Aqueous Phase Behavior of Phytantriol: Effect of Vitamin E Acetate and F127 Polymer on Liquid Crystal Nanostructure Y. Langmuir. 2006; 22:9512-9518.
  12. Adi H, Larson I, Chiou H, Young P, Traini D, Stewart P. Agglomerate Strength and Dispersion of Salmeterol Xinafoate from Powder Mixtures for Inhalation. Pharmaceutical Research. 2006; 23(11):2556-2565.
  13. Ralston J, Larson I, Rutland M, Feiler A, Kleijn M. Atomic Force Microscopy and Direct Surface Force Measurements. Pure and Applied Chemistry. 2005; 77(12):2149-2170.
  14. Islam N, Stewart PJ, Larson I, Hartley P. Lactose surface modification by decantation-are drug-fine lactose ratios the key to better dispersion of salmeterol xinafoate from lactose interactive mixtures? Pharmaceutical Research. 2004; 21(3):492-499.
  15. Larson I, Drummond CJ, Chan DYC, Grieser F. Direct force measurements between TiO2 surfaces. Journal of the American Chemical Society. 1993; 115:11885-90.
  16. Hartley PG, Larson I, Scales PJ. Electrokinetic and direct force measurements between silica and mica surfaces in dilute electrolyte solutions. Langmuir. 1997; 13:2207-14.
  17. Larson I, Drummond CJ, Chan DYC, Grieser F. Direct force measurements between dissimilar metal-oxides. Journal of Physical Chemistry. 1995; 99:2114-18.
  18. Larson I, Drummond CJ, Chan DYC, Grieser F.Direct force measurements between silica and alumina Langmuir. 1997; 13:2109-12.
  19. Sader J, Larson I, Mulvaney P, White LR. Method for the calibration of atomic force microscope cantilevers. Review of Scientific Instruments. 1995;66:3789-98.
  20. Milling AJ, Mulvaney P, Larson I. Direct measurement of repulsive van der Waals interactions using an atomic force microscope. Journal of Colloid & Interface Science. 1996;180:460-5.

External appointments

  • Victorian representative, Colloid and Surfaces Division, Royal Australian Chemical Institute