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Dr Edmund S Kostewicz

Image of Dr Edmund S Kostewicz

Project Coordinator, Centre for Drug Candidate Optimisation

BSc University of Adelaide
BSc(Hons) Flinders University
PhD University of South Australia

Telephone: +61 3 9903 9148
Fax: +61 3 9903 9052
Email: edmund.kostewicz@pharm.monash.edu.au

Centre for Drug Candidate Optimisation, Monash Institute of Pharmaceutical Sciences

Research interests

  • Biopharmaceutical aspects of drug absorption
  • Lead optimisation
  • Pre-clinical development of new drug candidates

Representative publications

  1. Vertzoni M, Fotaki N, Kostewicz E, Stippler E, Leuner C, Nicolaides E. et.al. Dissolution media simulating the intralumenal composition of the small intestine: physiological issues and practical aspects. Journal of Pharmacy & Pharmacology. 2004 Apr;5 6(4):453-62.
  2. Kostewicz ES, Wunderlich M, Brauns U, Becker R, Bock T, Dressman JB. Predicting the precipitation of poorly soluble weak bases upon entry in the small intestine. Journal of Pharmacy & Pharmacology. 2004 Jan; 56(1):43-51.
  3. Scholz A, Kostewicz E, Abrahamsson B, Dressman JB. Can the USP paddle method be used to represent in-vivo hydrodynamics?. Journal of Pharmacy & Pharmacology. 2003 Apr; 55(4):443-51.
  4. Kostewicz ES, Brauns U, Becker R, Dressman JB. Forecasting the oral absorption behavior of poorly soluble weak bases using solubility and dissolution studies in biorelevant media. Pharmaceutical Research. 2002 Mar; 19(3):345-9.
  5. Scholz A, Abrahamsson B, Diebold SM, Kostewicz E, Polentarutti BI, Ungell AL et.al . Influence of hydrodynamics and particle size on the absorption of felodipine in labradors. Pharmaceutical Research. 2002 Jan; 19(1):42-6.