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Centre for Drug Candidate Optimisation

About us

The Centre for Drug Candidate Optimisation (CDCO) is an innovative collaborative research centre that provides ADME lead optimisation advice and support for emerging drug discovery programs within biotechnology and pharmaceutical companies and not-for-profit research institutes.

Pharmacokinetics

Examination of the in vivo ADME properties of selected drug candidates.

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Drug metabolism

Utilisation of in vitro techniques to assess and predict the metabolic fate of new drug candiates.

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Formulation and physical chemistry

Assessment of the properties of drug candidates to identify problems with oral absorption, disposition and product formulation.

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Bioanalysis

Development of rapid, specific and quantitative LC-MS bioanalytical methods for the detection of drug candidates.

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Impact

More than 15 new drug candidates have progressed into clinical development through collaborative programmes with the CDCO.

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CDCO

Platforms