Synthetic medicinal chemistry honours projects for 2010

A₁AR allosteric enhancers as cardioprotective agents
Adenosine receptor agonists and allosteric enhancers as cardioprotective agents
Allosteric modulators for the acetylcholine muscarinic M2 receptor, an important GPCR
Anticancer drug discovery - asymmetric synthesis and structure-activity relationship studies of roseophilin
Anticancer drug discovery - targeting hypoxia
Anticancer drug discovery- synthesis and SAR studies of novel lamellarin analogues
Anticancer drug discover - synthesis and SAR studies of novel rocaglate analogues using a polycyclisation cascade
Brain uptake of a novel series of antipsychotic compounds
Dual inhibitors of RasGAP and ERK1 for maintenance of pluripotency of embryonic stem cells
Functionalised luminescent nanoparticles for multi-modal in vivo tumour imaging
Luminescent biosensors for monitoring kinase activity
Myxobacterial natural products as antibiotics against gram-negative 'superbugs'
New antimicrobials from the folate pathway: targeting hydroxymethyl pterin pyrophosphate kinase
New syntheses of pharmaceutical opiates
Novel colloidal carriers for siRNA - particle properties and in vivo pharmacokinetics
Novel fluorogenic reagents for bioconjungation
Novel inhibitors of phosphodiesterase-2
Novel luminescent probes for studying adenosine receptor-ligand interactions
Role of GSK3 inhibitors in stabilisation of embryonic stem cells and Isl1+ cardiovascular progenitors
Structural studies of P13 kinase catalysis and inhibitor bindings
Synthesis and biological evaluation of M3 muscarinic receptor antagonists on contractility in the prostate gland
Systemic distribution of albumin-siRNA conjugates
The role of Rho-associated kinase (ROCK1) inhibitors in survival of embryonic stem cells
The synthesis and pharmacological evaluation of potential monoacylglycerol lipase inhibitors